Consider how changes in the pharmacokinetic and pharmacodynamic processes might impact the patient’s recommended drug therapy.

Patient AO has a history of obesity and has recently gained 9 pounds. The patient has been diagnosed with hypertension and hyperlipidemia. Drugs currently prescribed include the following:

 Atenolol 12.5 mg daily

 Doxazosin 8 mg daily

Hydralazine 10 mg qid

 Sertraline 25 mg daily

Simvastatin 80 mg daily