describe the principle behind one method of detecting the histological abnormality

illustrate the pathological condition show the normal histology of the cell or tissue and abnormal and the detection method for example (EM . stain , lab ) in anatomic pathohistology there must be one image of healthy tissue and one image for unkealthy tissue to show the change should mention the prevalence and severity of the disease within the population must be lab detection where you must describe the principle behind one method of detecting the histological abnormality with images with figer numbers must be bibliography