Compare and contrast the similarities and differences between ramipril/metoprolol with respect to pharmacokinetics and pharmacodynamics.
COMPARE and CONTRAST the similarities and differences between ramipril/metoprolol with respect to pharmacokinetics and pharmacodynamics.
Use the non-proprietary (non-commercial) names for the drug pair throughout the essay. Apply resources such as journal articles, medical and scientific text books, and scientific web based resources (e.g. NIH website, American Heart Association website) to support your essay content. DO NOT use commercial non-government websites.
It is recommended to self-check your essay assignment by using the marking rubric provided.
The essay assignment will comprise;
1. A brief descriptive single short sentence title of approximately 10 words (see marking rubric for criteria);
2. Introduce both drugs and specify their actions and indications in a single paragraph;
3. The pharmacokinetics of each drug by comparing and contrasting the following;
a. Brief administration route of the drugs and then detail how the drugs are absorbed
b. Bioavailability and half-life of the drugs
c. Distribution of the drugs in the body
d. Metabolism of the drugs
e. Excretion of the drugs
4. Detail and compare the pharmocodynamics of the drugs. Include the following information:
a. Compare/Contrast the mechanism of action of the drugs. If this is currently unknown, what is it thought to be?
b. Identify the adverse drug reactions linked to the mechanism of action and explain why they occur.
Writing format. See notes under Presentation.
